منابع مشابه
Controlled Drug Release Asymptotics
The solution of Higushi’s model for controlled release of drugs is examined when the solubility of the drug in the polymer matrix is a prescribed function of time. A time-dependent solubility results either from an external control or from a change in pH due to the activation of pH immobilized enzymes. The model is described as a one-phase moving boundary problem which cannot be solved exactly....
متن کاملpH Sensitive Hydrogel Based Acrylic Acid for Controlled Drug Release
Hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. The present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on pH-sensitive polymers such as poly (acrylic acid). Poly (acrylic acid), p(AA), hydrogel has been synthesized by radical po...
متن کاملDrug Delivery: Controlled Release
Over the past decades, the treatment of illness has been accomplished by administering drugs to the human body via various pharmaceutical dosage forms, like tablets. These traditional pharmaceutical products are still commonly seen today in the prescription and over-the-counter drug marketplace. To achieve and maintain the drug concentration in the body within the therapeutic range required for...
متن کاملLITERATURE ON CONTROLLED RELEASE DRUG DELIVERY SYSTEMS (MICROCAPSULES AND MATRIX TABLETS) Controlled release drug delivery systems
Controlled release drug delivery systems 1 are those dosage formulations designed to release an active ingredient at rates, which differ significantly from their corresponding conventional dosage forms. The controlled release drug delivery systems are aimed at controlling the rate of drug delivery, sustaining the duration of therapeutic activity and/or targeting the delivery of the drug to a ti...
متن کاملDesign of Controlled- Release Drug Delivery Systems
22.1 PHYSICOCHEMICAL PROPERTIES OF 22.7 BIODEGRADABLE/ERODIBLE DRUG 22.2 DELIVERY SYSTEMS 22.9 22.2 ROUTES OF DRUG 22.8 OSMOTIC PUMP 22.10 ADMINISTRATION 22.3 22.9 ION EXCHANGE RESINS 22.11 22.3 PHARMACOLOGICAL AND 22.10 NEW MACROMOLECULAR DELIVERY BIOLOGICAL EFFECTS 22.4 APPROACHES 22.12 22.4 PRODRUG 22.4 22.11 CONCLUSION 22.14 22.5 DIFFUSION-CONTROLLED DELIVERY REFERENCES 22.14 SYSTEMS 22.5 2...
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ژورنال
عنوان ژورنال: SIAM Journal on Applied Mathematics
سال: 1998
ISSN: 0036-1399,1095-712X
DOI: 10.1137/s0036139995293269